{"product_id":"mots-c","title":"Mots-c","description":"\u003ch2\u003eMitochondrial-Derived Peptide (MDP) Research Compound\u003c\/h2\u003e\n\u003cp\u003eMOTS-C (10mg\/40mg) will be supplied with fast domestic shipping to all states and territories.\u003c\/p\u003e\n\u003cp\u003eMOTS-C is an endogenous mitochondrial-derived peptide (MDP) encoded in the mitochondrial genome — unusual among mammalian peptides, which are typically nuclear-encoded. First characterised in 2015 by researchers at the University of Southern California, MOTS-C has become a central focus of metabolic and longevity research.\u003c\/p\u003e\n\u003cp\u003ePlasma MOTS-C levels decline with age and correlate with insulin resistance, reduced exercise capacity, and metabolic dysfunction in human observational studies. Mechanistically, MOTS-C translocates from mitochondria to nucleus under metabolic stress and activates AMPK — the master cellular energy regulator also activated by exercise and caloric restriction.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsulin Sensitivity\u003c\/strong\u003e — Studied for improved glucose uptake and insulin signalling in type 2 diabetes and metabolic syndrome models\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExercise Adaptation\u003c\/strong\u003e — Studied for endurance and training response in preclinical models\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Ageing\u003c\/strong\u003e — Plasma MOTS-C correlates with biological age markers; studied in longevity research\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAMPK Activation\u003c\/strong\u003e — Studied for cellular energy regulation via AMPK-mediated pathways\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eObesity Models\u003c\/strong\u003e — Studied in high-fat diet models for reversal of insulin resistance and improved fat metabolism\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSupplied as lyophilized powder at ≥99% purity, verified by HPLC and mass spectrometry. 10mg per vial. Fast domestic shipping across Australia, with batch-specific CoA information available in our CoA Library.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e⚠ For in-vitro research and laboratory use only. Not for human consumption.\u003c\/em\u003e\u003c\/p\u003e","brand":"Glow Industries","offers":[{"title":"10mg vial only","offer_id":48655604187361,"sku":null,"price":80.0,"currency_code":"AUD","in_stock":true},{"title":"10mg vial \u0026 kit","offer_id":48655604220129,"sku":null,"price":100.0,"currency_code":"AUD","in_stock":true},{"title":"40mg vial only","offer_id":48655604252897,"sku":null,"price":160.0,"currency_code":"AUD","in_stock":true},{"title":"40mg vial \u0026 kit","offer_id":48655604285665,"sku":null,"price":180.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/2990\/5377\/files\/IMG-8335.png?v=1784023902","url":"https:\/\/www.glowindustries.com.au\/products\/mots-c","provider":"Glow Industries","version":"1.0","type":"link"}